Recently, a research program led by ZHANG Bingbo in the research team led by SHI Donglu from the Biomedical Engineering and Nanoscience Research Institute, Tongji University has made ultra-small nanoparticles containing gadolinium sulfide by using protein-specific structure function domain and amino acid sequence in situ green bionic synthesis for the tumor in vivo function domain/ magnetic dual-mode imaging, and imaging guidance of tumor ablation of light and heat efficient treatment.